C. reflexa is a treasured medicinal herb and widely used in conventional medicinal system of various Asian countries including China, India, Bangladesh, and Thailand for treating multiple disorders (122). It is called a miracle therapeutic plant in the ethnobotany, and a wide array of chemical compounds has been isolated with diverse medicinal properties (123). C. reflexa whole plant is used to treat conjunctivitis, respiratory disorders, piles, ulcers, and stomach problems (124). The paste of whole plant mixed with latex Carica papaya causes abortions (125). In rural areas of India its juice is used against jaundice. Paste of plant is effective to treat headache, gout, and rheumatism (67, 126-128). Plant juice mixed with other decoctions is purgative. Seeds of C. reflexa are carminative, anthelmintic, alterative, emmenagogue, sedative, and diuretic. It is effective against warts (116, 129). Leaves are used to treat eczema, scabies, cold, and to induce sterility (18, 130). Rabha tribes of west Bengal use the whole plant to treat leucorrhoea (131). It is applied internally to cure protracted fevers and externally on itchy skin. The plant is frequently used in Ayurvedic medicine to give relief in urinating difficulties, muscle pain, and coughs (132, 133). Pills prepared from the dried plant are used for treatment of tuberculosis (89). Its stem is a blood purifier, good for brain and fever (134-135). Tribal people use its various parts to treat fits, insanity, melancholy, and to control fertility (15). It is commonly used in veterinary medicines as poultice and sprains. The powder is used as astringent and diaphoretic for cattle (136-137).
Green synthesised extracts adopted by different researchers for the synthesis of AgNps includes cocoa bean extract [13], miracle fruit plant [14], Petiveria alliacea L. Leaf extract [15], agriwastes, enzymes and pigments [16], Buchholzia coriacea, Cocoa pod husk [17, 18], Cola nitida [19, 20], Persea Americana fruit peel [21], Opuntia ficaus-indica [22], Chasmanthera dependens [23] and so on. The biological method has several advantageous features for instance non-toxic, ecofriendly acceptable route, economical, very much feasible reaction conditions and such others. Bimolecular systems that are associated with plants like protein, Flavanoids, polyphenols not only acts as antioxidants but also as capping agents in overlaying the nanoparticles.
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